This study, funded as part of the Robert Wood Johnson Foundation’s Systems for Action research program, pilot tests a novel community-embedded, technology-supported overdose response intervention that aligns medical care, public health, and social service systems to improve outcomes for persons following the experience of an overdose among people living in the Skid Row area of Los Angeles, CA. The intervention proposes to dismantle the structural racism that channels marginalized communities into overburdened low-resource medical systems with limited capacity to address underlying health and social needs, and that excludes these communities from having a voice in how these systems operate.